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The degree of phase II conjugation, typically encompassing sulfation, glucuronidation and methylation (see section 6.1 Pre-systemic metabolism: role of gut microbiota), is high for individual molecules (Table 3)

GSH is the predominant intracellular form, which acts as a strong antioxidant and defends against toxic compounds and xenobiotics

[DOI] [PMC free article] [PubMed] [Google Scholar] 157.Bettermann E.L., Hartman T.J., Easley K.A., Ferranti E.P., Jones D.P., Quyyumi A.A., Vaccarino V., Ziegler T.R., Alvarez J.A

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness